![]() You'll need to stay in a special germ-free hospital room during the first few weeks after the transplant. infections – a lack of white blood cells and any immunosuppressant medicine you're taking will mean your body is not able to fight off infections.excessive bleeding or bruising caused by a lack of clotting cells called platelets you may need transfusions of platelets if this is a problem.iron deficiency anaemia – a lack of red blood cells that can make you feel tired and short of breath this may be treated with regular blood transfusions.Until your body starts being able to produce healthy blood cells again, you may be at risk of: These will eventually be replaced by the transplanted stem cells, although this process can take several weeks or more. In preparation for a stem cell transplant, you'll need to have chemotherapy to destroy the damaged or diseased blood cells. GvHD can be treated with medicines that suppress your immune system and stop the transplanted stem cells attacking the rest of your body. Tell your treatment team if you develop these symptoms. yellowing of the whites of the eyes and the skin, although this may be less obvious on brown or black skin ( jaundice).The condition is usually mild but can sometimes be life-threatening. GvHD can happen within a few months of the transplant or develop several months, or occasionally a year or 2, later. This is known as graft versus host disease (GvHD). Sometimes, the transplanted cells recognise the recipient's cells as "foreign" and attack them. ![]() People receiving transplants of their own stem cells (autologous transplants) are also less likely to experience serious side effects. Generally speaking, younger people who do not have any other serious conditions or those who receive transplants from a closely matched sibling are less likely to experience serious problems. You may wish to discuss them with your treatment team and your family. ![]() It's important that you're aware of both the risks and possible benefits before treatment begins. Ĭelebrating 50 Years of Stem Cell Transplantation: Learn about the history, progress, and innovation in the adult stem cell transplantation program over the past 50 years.Stem cell or bone marrow transplants are complex treatments that carry a significant risk of serious complications. Learn more about stem cell transplants from the Stem Cell Transplantation Program at Dana-Farber/Brigham and Women’s Cancer Center. With time, many of these side effects subside as your immune system recovers. It is important to share information about the side effects that you experience with your care team. Many patients also continue to deal with:įor allogeneic transplant patients, it is important to be aware of possible signs of graft-versus-host disease (GVHD), which may include skin rashes or skin changes, yellowing of the skin or eyes, excessive dryness or pain in the mouth, joint pain, or eye dryness. The most common side effects after transplant are: Some of these side effects may persist for a period of time even after you return home. Most patients are very tired and get warn out with very little activity while their counts are low. You may also develop skin rashes, as well as mucositis, which makes it difficult to eat or drink.ĭiarrhea and lack of appetite are also common. The phase after the stem cell infusion is called engraftment, when the transplanted stem cells begin to make new blood components - including red blood cells, platelets, and other components of the immune system - within your body.įrom the time you receive stem cells until engraftment, you may experience side effects including nausea, and trouble sleeping. In some cases, intravenous fluids or medication can be given to help prevent or reduce these effects.
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